Paraneoplastic neurological syndrome associated with a pulmonary carcinoid tumor: a case report

Abstract

Paraneoplastic neurological syndromes (PNS) are a rare and heterogeneous group of immune-mediated neurological disorders. We report the case of a 32-year-old woman with progressive and severely disabling neurological symptoms. After excluding alternative causes, she was diagnosed with an atypical pulmonary carcinoid tumor. Surgical resection led to partial clinical improvement. This case underscores the importance of considering PNS in patients with unexplained neurological symptoms and highlights the need to investigate for underlying neoplasms as a potential trigger.

Description

Keywords

antibodies, carcinoid tumor, case reports, nervous system, neuroendocrine tumors, paraneoplastic syndromes.

Citation

Arroyave-Guerrero Y, García-Herreros LG, Granada-Camacho J. Paraneoplastic neurological syndrome associated with a pulmonary carcinoid tumor: a case report. J Surg Case Rep. 2025 Aug 29;2025(8):rjaf559. doi: 10.1093/jscr/rjaf559. PMID: 40894939; PMCID: PMC12396628.

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