Artículos

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14595/803

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Recurrence After Biopsy-Confirmed Cervical High-Grade Intraepithelial Lesion Followed by Negative Conization: A Systematic Review and Meta-analysis
(Journal of Lower Genital Tract Disease, 2024-01-01) Viveros-Carreño, David; Mora-Soto, Nathalia; Rodríguez, Juliana; Rauh-Hain, José Alejandro; Ramírez, Pedro T.; López Varón, Melissa; Krause, Kate J.; Grillo-Ardila, Carlos Fernando; Jeronimo, Jose; Pareja, René
The aim of the study is to assess the recurrence rate (as cervical intraepithelial neoplasia 2+ [CIN2+]) in patients who had a confirmed high-grade squamous intraepithelial lesion (CIN2–3) in a cervical biopsy specimen followed by a negative conization specimen.
Morbidity of radical surgery and postoperative radiotherapy in cervical cancer
(2024-12-13) Nathalia Mora-Soto; Carolina Morante-Caicedo; Maria Caicedo-Martínez; David Viveros-Carreño; Emmanuel Sánchez Diaz; Juliana Rodríguez; Santiago Vieira; Jonathan A. Peralta; Nadeem R. Abu-Rustum; Rene Pareja
Cervical cancer is among the most common cancers affecting women worldwide. The standard treatment for early-stage cervical cancer (International Federation of Gynecology and Obstetrics [FIGO] 2018 stages IA1–IB2, IIA1) typically involves a rad ical or simple hysterectomy with lymph node assessment. Postoperative management may include observation or tailored adjuvant therapy, such as radiotherapy or chemo radiotherapy, depending on individual pathological risk factors. However, these inter ventions are associated with significant complications: surgical management can lead to urinary and sexual dysfunction, lymphocysts, and lower limb lymphedema, while radiotherapy may cause genitourinary, gastrointestinal, and sexual toxicities. Less radical surgery for selected cases could reduce surgical morbidity and advances in radiotherapy techniques, such as intensity-modulated radiotherapy, volumetric mod ulated arc therapy, and other three-dimensional conformal radiation therapies, have the potential to enhance precision and reduce toxicity. Nonetheless, the morbidity associated with combining radical surgery and adjuvant (chemo)radiotherapy remains an area of uncertainty, particularly in light of these emerging technologies. Most cur rent data on this topic derive from retrospective studies involving heterogeneous populations and inconsistent quality-of-life assessment methods. Prospective studies employing standardized morbidity assessment tools are essential to determine the true impact of combined treatments compared to single-modality approaches. Future research should prioritize understanding the long-term effects of these treatment strategies, aiming to minimize adverse outcomes while maintaining optimal oncologi cal control.
Highlights from the third Colombian conference on women’s cancers
(William Andrés Piñeros Castillo, 2025-05-02) Santía María Clara; Alvarenga-Bezerra Vanessa; Piñeros Castillo William Andrés; Morante-Caicedo Carolina; Heng-Cheng Hsu; Noll Florencia
This report covers the “Third Colombian Conference on Women’s Cancers” held in Medellín, Colombia on 31 January and 1 February 2025. The meeting gathered over 345 participants from 18 countries. The event featured 32 speakers, including 21 national and 11 international experts. The conference provided an educational experience focused on the latest advances in gynecologic oncology and breast cancer. The program featured both local and international speakers and addressed key topics in our field.

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